Lamin B2 Protein (LMNB2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724479

Recombinant Lamin B2 protein expressed in HEK-293 Cells.

Quick Overview for Lamin B2 Protein (LMNB2) (Myc-DYKDDDDK Tag) (ABIN2724479)

Target: Lamin B2 (LMNB2)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Lamin B2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Lamin-B2 (LMNB2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Lamin B2 (LMNB2)

Alternative Name: Lamin-b2 (Lmnb2)

Background: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Molecular Weight: 67.5 kDa

NCBI Accession: NP_116126

Pathways: Apoptosis, Caspase Cascade in Apoptosis