LIN7C Protein (Myc-DYKDDDDK Tag)
Quick Overview for LIN7C Protein (Myc-DYKDDDDK Tag) (ABIN2724765)
Target
Protein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This LIN7C protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human LIN7C protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Lin-7 Homolog C (LIN7C) (AA 1-197) protein (GST tag)
LIN7C Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Lin-7 Homolog C (LIN7C) (AA 1-197) protein (His-IF2DI Tag)LIN7C Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Lin-7 Homolog C (LIN7C) (AA 1-197) protein (His tag)LIN7C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- LIN7C (Lin-7 Homolog C (LIN7C))
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Alternative Name
- Lin7c
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Background
- Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. [UniProtKB/Swiss-Prot Function]
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Molecular Weight
- 21.7 kDa
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NCBI Accession
- NP_060832
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Pathways
- Synaptic Membrane
Target
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