LPIN3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for LPIN3 Protein (Myc-DYKDDDDK Tag) (ABIN2724799)
Target
See all LPIN3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This LPIN3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Lipin 3 (LPIN3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Lipin 3 (LPIN3) (AA 1-848) protein (His tag)
custom-made LPIN3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Lipin 3 (LPIN3) (AA 1-851) protein (His tag)custom-made LPIN3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- LPIN3 (Lipin 3 (LPIN3))
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Background
- The protein encoded by this gene is a member of the lipin family of proteins, and all family members share strong homology in their C-terminal region. This protein is thought to form hetero-oligomers with other lipin family members, while one family member, lipin 1, can also form homo-oligomers. This protein contains conserved motifs for phosphatidate phosphatase 1 (PAP1) activity as well as a domain that interacts with a transcriptional co-activator. Lipin complexes act in the cytoplasm to catalyze the dephosphorylation of phosphatidic acid to produce diacylglycerol, which is the precursor of both triglycerides and phospholipids. Lipin complexes are also thought to regulate gene expression as transcriptional co-activators in the nucleus. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 93.4 kDa
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NCBI Accession
- NP_075047
Target
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