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Lipin 1 Protein (LPIN1) (Myc-DYKDDDDK Tag)

This Recombinant Lipin 1 protein is expressed in HEK-293 Cells.
Catalog No. ABIN2724880

Quick Overview for Lipin 1 Protein (LPIN1) (Myc-DYKDDDDK Tag) (ABIN2724880)

Target

See all Lipin 1 (LPIN1) Proteins
Lipin 1 (LPIN1)

Protein Type

Recombinant

Origin

  • 4
  • 4
  • 2
Human

Source

  • 4
  • 2
  • 2
  • 2
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Lipin 1 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human LPIN1 / Lipin-1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
    Origin
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $13,686.36
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Lipin 1 (LPIN1)

    Alternative Name

    Lpin1,lipin-1

    Background

    This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

    Molecular Weight

    98.5 kDa

    NCBI Accession

    NP_663731

    Pathways

    Monocarboxylic Acid Catabolic Process
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