LZTS2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725089

This Recombinant LZTS2 protein is produced in HEK-293 Cells.

Quick Overview for LZTS2 Protein (Myc-DYKDDDDK Tag) (ABIN2725089)

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This LZTS2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human LZTS2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Alternative Name: Lzts2

Background: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 72.6 kDa

NCBI Accession: NP_115805