MBNL1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for MBNL1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2725580)
Target
See all MBNL1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This MBNL1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MBNL1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Muscleblind-like Protein 1 (MBNL1) (AA 1-341) protein (His tag)
custom-made MBNL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Muscleblind-like Protein 1 (MBNL1) (AA 1-388) protein (His tag)custom-made MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 6) (Active) protein (Myc-DYKDDDDK Tag)MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Muscleblind-like Protein 1 (MBNL1) (AA 1-343) protein (GST tag)MBNL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Muscleblind-like Protein 1 (MBNL1) (AA 1-382) protein (GST tag)MBNL1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 7) protein (Myc-DYKDDDDK Tag)MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)MBNL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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Alternative Name
- Mbnl1
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Background
- This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
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Molecular Weight
- 40.8 kDa
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NCBI Accession
- NP_066368
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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