Menin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for Menin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2725822)
Target
See all Menin (MEN1) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This Menin protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Menin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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Alternative Name
- Menin
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Background
- This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 67.3 kDa
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NCBI Accession
- NP_570711
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Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
Target
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