Moesin Protein (MSN) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726221

This Recombinant Moesin protein is expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for Moesin Protein (MSN) (Myc-DYKDDDDK Tag) (ABIN2726221)

Target: Moesin (MSN)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Moesin protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Moesin protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Miyaji, Shahrizaila, Umapathi, Chan, Hirata, Yuki: "Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?" in: Human immunology, Vol. 75, Issue 11, pp. 1089-91, (2015) (PubMed).

Target Details

Target: Moesin (MSN)

Alternative Name: Moesin

Background: Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

Molecular Weight: 67.6 kDa

NCBI Accession: NP_002435

Pathways: Asymmetric Protein Localization