MTA1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for MTA1 Protein (Myc-DYKDDDDK Tag) (ABIN2726481)
Target
See all MTA1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This MTA1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MTA1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Metastasis Associated 1 (MTA1) (AA 601-700) protein (GST tag)
MTA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Metastasis Associated 1 (MTA1) (AA 1-255) protein (GST tag)MTA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Metastasis Associated 1 (MTA1) (AA 1-429), (full length) protein (His-SUMO Tag)MTA1 Origin: Acinetobacter baumannii Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MTA1 (Metastasis Associated 1 (MTA1))
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Alternative Name
- Mta1
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Background
- This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 80.6 kDa
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NCBI Accession
- NP_004680
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Pathways
- Chromatin Binding
Target
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