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NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

This Recombinant NECAB3 protein is produced in HEK-293 Cells.
Catalog No. ABIN2727054
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2727054)

Target

See all NECAB3 Proteins
NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Protein Type

Recombinant

Origin

  • 2
  • 1
  • 1
Human

Source

  • 2
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This NECAB3 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human NECAB3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

    Alternative Name

    Necab3

    Background

    The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    40.6 kDa

    NCBI Accession

    NP_112508
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