NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2727054)
Target
See all NECAB3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This NECAB3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human NECAB3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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Alternative Name
- Necab3
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Background
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 40.6 kDa
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NCBI Accession
- NP_112508
Target
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