Neuroligin 3 Protein (NLGN3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2727167

Recombinant Neuroligin 3 protein expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for Neuroligin 3 Protein (NLGN3) (Myc-DYKDDDDK Tag) (ABIN2727167)

Target: Neuroligin 3 (NLGN3)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This Neuroligin 3 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Neuroligin 3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Venkatesh, Johung, Caretti, Noll, Tang, Nagaraja, Gibson, Mount, Polepalli, Mitra, Woo, Malenka, Vogel, Bredel, Mallick, Monje: "Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion." in: Cell, Vol. 161, Issue 4, pp. 803-16, (2015) (PubMed).

Target Details

Target: Neuroligin 3 (NLGN3)

Alternative Name: Neuroligin 3

Background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 91.4 kDa

NCBI Accession: NP_061850

Pathways: Synaptic Membrane