OCRL Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2727866

Recombinant OCRL protein expressed in HEK-293 Cells.

Quick Overview for OCRL Protein (Transcript Variant B) (Myc-DYKDDDDK Tag) (ABIN2727866)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant B

Purification tag / Conjugate: This OCRL protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human OCRL (transcript variant b) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Alternative Name: Ocrl

Background: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Molecular Weight: 103 kDa

NCBI Accession: NP_001578

Pathways: Inositol Metabolic Process