OPTN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for OPTN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2727924)
Target
See all OPTN ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This OPTN protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Optineurin / HIP7 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Optineurin (OPTN) (AA 1-571) protein (GST tag)
OPTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Optineurin (OPTN) (AA 1-577) protein (GST tag)OPTN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Optineurin (OPTN) (AA 16-223) protein (His-IF2DI Tag)OPTN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- OPTN (Optineurin (OPTN))
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Alternative Name
- Optineurin,hip7
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Background
- This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
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Molecular Weight
- 65.7 kDa
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NCBI Accession
- NP_001008212
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Pathways
- M Phase
Target
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