PARN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for PARN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2728260)
Target
See all PARN ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This PARN protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PARN (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Poly A Specific Ribonuclease (PARN) (AA 1-639) protein (GST tag)
PARN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Poly A Specific Ribonuclease (PARN) (AA 1-639), (full length) protein (His tag)PARN Origin: Human Host: Yeast Recombinant > 90 % SDS
Poly A Specific Ribonuclease (PARN) (AA 1-639), (full length) protein (His tag)PARN Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PARN (Poly A Specific Ribonuclease (PARN))
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Alternative Name
- Parn
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Background
- The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 73.3 kDa
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NCBI Accession
- NP_002573
Target
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