PDE1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
This Recombinant PDE1A protein is expressed in HEK-293 Cells.
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Catalog No. ABIN2728480
$1,112.40
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20 μg
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United States
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Quick Overview for PDE1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2728480)
Target
See all PDE1A Proteins
PDE1A
(Phosphodiesterase 1A (PDE1A))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This PDE1A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PDE1A (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Phosphodiesterase 1A (PDE1A) (AA 1-545) protein (GST tag)
PDE1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PDE1A (Phosphodiesterase 1A (PDE1A))
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Alternative Name
- Pde1a
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Background
- Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1 MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109] Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009].
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Molecular Weight
- 62.1 kDa
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NCBI Accession
- NP_005010
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Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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