PDE4A Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
This Recombinant PDE4A protein is expressed in HEK-293 Cells and has been mentioned in 1 publication.
1 image
(1 reference)
Catalog No. ABIN2728507
$1,112.40
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20 μg
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United States
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Quick Overview for PDE4A Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag) (ABIN2728507)
Target
See all PDE4A Proteins
PDE4A
(phosphodiesterase 4A, CAMP-Specific (PDE4A))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 4
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Purification tag / Conjugate
- This PDE4A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PDE4A (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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phosphodiesterase 4A, CAMP-Specific (PDE4A) (AA 1-647) protein (GST tag)
PDE4A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).
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- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
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Alternative Name
- Pde4a
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Background
- The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
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Molecular Weight
- 72 kDa
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NCBI Accession
- NP_006193
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Pathways
- cAMP Metabolic Process
Target
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