PDE4A Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all PDE4A Proteins
- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 4
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDE4A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDE4A (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDE4A Protein
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phosphodiesterase 4A, CAMP-Specific (PDE4A) (AA 1-886) protein (His tag)
custom-made PDE4A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
phosphodiesterase 4A, CAMP-Specific (PDE4A) (AA 1-844) protein (His tag)custom-made PDE4A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
phosphodiesterase 4A, CAMP-Specific (PDE4A) (AA 1-647) protein (GST tag)PDE4A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).
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: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).
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- Target
- PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))
- Alternative Name
- Pde4a (PDE4A Products)
- Background
- The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
- Molecular Weight
- 72 kDa
- NCBI Accession
- NP_006193
- Pathways
- cAMP Metabolic Process
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