Quick Overview for PRPH2 Protein (Myc-DYKDDDDK Tag) (ABIN2728685)
Target
See all PRPH2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PRPH2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Peripherin-2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Peripherin 2 (Retinal Degeneration, Slow) (PRPH2) (AA 1-346) protein (His tag)
custom-made PRPH2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Peripherin 2 (Retinal Degeneration, Slow) (PRPH2) (AA 1-346) protein (His tag)custom-made PRPH2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PRPH2 (Peripherin 2 (Retinal Degeneration, Slow) (PRPH2))
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Alternative Name
- Peripherin-2
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Background
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic.
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Molecular Weight
- 39.1 kDa
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NCBI Accession
- NP_000313
Target
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