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PGPEP1 Protein (Myc-DYKDDDDK Tag)

This Recombinant PGPEP1 protein is produced in HEK-293 Cells.
Catalog No. ABIN2728797

Quick Overview for PGPEP1 Protein (Myc-DYKDDDDK Tag) (ABIN2728797)

Target

See all PGPEP1 Proteins
PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))

Protein Type

Recombinant

Origin

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Human

Source

  • 15
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This PGPEP1 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human PGPEP1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
    Origin
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $12,595.45
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    PGPEP1 (Pyroglutamyl-Peptidase I (PGPEP1))

    Alternative Name

    Pgpep1

    Background

    The gene encodes a cysteine protease and member of the peptidase C15 family of proteins. The encoded protein cleaves amino terminal pyroglutamate residues from protein substrates including thyrotropin-releasing hormone and other neuropeptides. Expression of this gene may be downregulated in colorectal cancer, while activity of the encoded protein may be negatively correlated with cancer progression in colorectal cancer patients. Activity of the encoded protease may also be altered in other disease states including in liver cirrhosis, which is associated with reduced protease activity, and in necrozoospermia, which is associated with elevated protease activity.

    Molecular Weight

    23 kDa

    NCBI Accession

    NP_060182
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