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PNMA3 Protein (His tag)

PNMA3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729242
  • Target See all PNMA3 Proteins
    PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    Human
    Source
    • 2
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This PNMA3 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PNMA3 / MA3 (full length, N-term HIS tag) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PNMA3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))
    Alternative Name
    Pnma3,ma3 (PNMA3 Products)
    Synonyms
    MA3 Protein, MA5 Protein, RGD1563752 Protein, PNMA family member 3 Protein, paraneoplastic antigen MA3 Protein, paraneoplastic Ma antigen 3 Protein, PNMA3 Protein, Pnma3 Protein
    Background
    The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    52.2 kDa
    NCBI Accession
    NP_037496
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