PNMA3 Protein (His tag)
Quick Overview for PNMA3 Protein (His tag) (ABIN2729242)
Target
See all PNMA3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PNMA3 protein is labelled with His tag.
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Characteristics
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- Recombinant human PNMA3 / MA3 (full length, N-term HIS tag) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
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Paraneoplastic Antigen MA3 (PNMA3) (AA 1-466) protein (His tag)
custom-made PNMA3 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Paraneoplastic Antigen MA3 (PNMA3) (AA 1-463) protein (His tag)custom-made PNMA3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the N-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PNMA3 (Paraneoplastic Antigen MA3 (PNMA3))
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Alternative Name
- Pnma3,ma3
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Background
- The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 52.2 kDa
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NCBI Accession
- NP_037496
Target
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