PRDM12 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729559

This Recombinant PRDM12 protein is produced in HEK-293 Cells.

Quick Overview for PRDM12 Protein (Myc-DYKDDDDK Tag) (ABIN2729559)

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This PRDM12 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human PRDM12 / PFM9 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Alternative Name: Prdm12,pfm9

Background: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN&aposs) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.

Molecular Weight: 40.2 kDa

NCBI Accession: NP_067632