PBX1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PBX1 Protein (Myc-DYKDDDDK Tag) (ABIN2729562)
Target
See all PBX1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PBX1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Pre-B-cell leukemia homeobox 1 (PBX1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 213-321) protein (GST tag)
PBX1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1) (AA 136-430) protein (His tag)PBX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
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Alternative Name
- Pre-B-Cell Leukemia Homeobox 1 (Pbx1)
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Background
- This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(119) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 46.4 kDa
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NCBI Accession
- NP_002576
Target
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