PRELP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729749

This Recombinant PRELP protein is expressed in HEK-293 Cells.

Quick Overview for PRELP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2729749)

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This PRELP protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Prolargin / PRELP (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Alternative Name: Prolargin,prelp

Background: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Molecular Weight: 41.6 kDa

NCBI Accession: NP_958505

Pathways: Glycosaminoglycan Metabolic Process