PROP1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729760

This Recombinant PROP1 protein is produced in HEK-293 Cells. There is 1 publication available.

Quick Overview for PROP1 Protein (Myc-DYKDDDDK Tag) (ABIN2729760)

Target: PROP1 (PROP Paired-Like Homeobox 1 (PROP1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This PROP1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human PROP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Bando, Iguchi, Fukuoka, Yamamoto, Hidaka-Takeno, Okimura, Matsumoto, Suda, Nishizawa, Takahashi, Tojo, Takahashi: "Involvement of PIT-1-reactive cytotoxic T lymphocytes in anti-PIT-1 antibody syndrome." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. E1744-9, (2014) (PubMed).

Target Details

Target: PROP1 (PROP Paired-Like Homeobox 1 (PROP1))

Alternative Name: Prop1

Background: This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.

Molecular Weight: 24.8 kDa

NCBI Accession: NP_006252