RHOC Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730852

This Recombinant RHOC protein is produced in HEK-293 Cells.

Quick Overview for RHOC Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2730852)

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This RHOC protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human RhoC (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Alternative Name: Rhoc

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 21.8 kDa

NCBI Accession: NP_001036143

Pathways: WNT Signaling, Cell-Cell Junction Organization