Rhotekin Protein (RTKN) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for Rhotekin Protein (RTKN) (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2730883)
Target
See all Rhotekin (RTKN) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This Rhotekin protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Rhotekin / RTKN (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Rhotekin (RTKN) (AA 451-549) protein (GST tag)
RTKN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Rhotekin (RTKN) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)RTKN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Rhotekin (RTKN)
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Alternative Name
- Rhotekin,rtkn
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Background
- This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 61 kDa
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NCBI Accession
- NP_149035
Target
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