RIPK3 Protein (GST tag)

Catalog No. ABIN2730958

This Recombinant RIPK3 protein is expressed in Insect cells (Sf9).

Quick Overview for RIPK3 Protein (GST tag) (ABIN2730958)

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Protein Type: Recombinant

Origin: Human

Source: Insect cells (Sf9)

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This RIPK3 protein is labelled with GST tag.

Characteristics:

• Recombinant human RIPK3 / RIP3 (full length, N-term GST tag, C-term His tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 300 mM NaCl,10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Alternative Name: Ripk3,rip3

Background: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Molecular Weight: 56.7 kDa

NCBI Accession: NP_006862

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades