SAP18 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731387

This Recombinant SAP18 protein is expressed in HEK-293 Cells.

Quick Overview for SAP18 Protein (Myc-DYKDDDDK Tag) (ABIN2731387)

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This SAP18 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human SAP18 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: Sap18

Background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

Molecular Weight: 17.4 kDa

NCBI Accession: NP_005861