Senataxin (SETX) protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731631

Product Details

Target: Senataxin (SETX)

Protein Type: Recombinant

Origin: Human

Source: HEK-293T Cells

Purification tag / Conjugate: Myc-DYKDDDDK Tag

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Senataxin (SETX) protein expressed in HEK293 cell.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris-HCl, pH 7.3, 100 mM glycine, and 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Senataxin (SETX)

Abstract: SETX Products

Synonyms: ALS4 Protein, SETX Protein, wu:fj92h09 Protein, AOA2 Protein, SCAR1 Protein, bA479K20.2 Protein, Als4 Protein, Sen1 Protein, AW060766 Protein, mKIAA0625 Protein, A130090N03 Protein, A930037J23Rik Protein, RGD1565575 Protein, senataxin Protein, SETX Protein, setx Protein, Setx Protein

Background: This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Molecular Weight: 57.8 kDa

NCBI Accession: NP_055861