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Septin 5 Protein (SEPT5) (Myc-DYKDDDDK Tag)

This Recombinant Septin 5 protein is produced in HEK-293 Cells.
Catalog No. ABIN2731689

Quick Overview for Septin 5 Protein (SEPT5) (Myc-DYKDDDDK Tag) (ABIN2731689)

Target

See all Septin 5 (SEPT5) Proteins
Septin 5 (SEPT5)

Protein Type

Recombinant

Origin

  • 8
  • 3
  • 1
Human

Source

  • 5
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Septin 5 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human Septin-5 (SEPT5) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Septin 5 (SEPT5)

    Alternative Name

    Septin-5 (Sept5)

    Background

    This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

    Molecular Weight

    42.6 kDa

    NCBI Accession

    NP_002679

    Pathways

    Synaptic Vesicle Exocytosis
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