SERPINB6 Protein (Myc-DYKDDDDK Tag)
Quick Overview for SERPINB6 Protein (Myc-DYKDDDDK Tag) (ABIN2731817)
Target
See all SERPINB6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SERPINB6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SERPINB6 / PI6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))
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Alternative Name
- Serpinb6,pi6
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Background
- The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
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Molecular Weight
- 42.4 kDa
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NCBI Accession
- NP_004559
Target
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