SHOX2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732009

Recombinant SHOX2 protein expressed in HEK-293 Cells.

Quick Overview for SHOX2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2732009)

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 3

Purification tag / Conjugate: This SHOX2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human SHOX2 / SHOT (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Alternative Name: Shox2,shot

Background: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight: 33.4 kDa

NCBI Accession: NP_001157150

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development