Spastin Protein (SPAST) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732512

This Recombinant Spastin protein is expressed in HEK-293 Cells.

Quick Overview for Spastin Protein (SPAST) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2732512)

Target: Spastin (SPAST)

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 1

Purification tag / Conjugate: This Spastin protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Spastin / SPAST (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Spastin (SPAST)

Alternative Name: Spastin,spast

Background: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

Molecular Weight: 67 kDa

NCBI Accession: NP_055761

Pathways: Microtubule Dynamics, M Phase, Regulation of Cell Size