SPATA18 Protein (Myc-DYKDDDDK Tag)
Quick Overview for SPATA18 Protein (Myc-DYKDDDDK Tag) (ABIN2732514)
Target
See all SPATA18 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SPATA18 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SPATA18 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SPATA18 (Spermatogenesis Associated 18 (SPATA18))
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Alternative Name
- Spata18
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Background
- This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 60.9 kDa
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NCBI Accession
- NP_660306
Target
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