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SPATA18 Protein (Myc-DYKDDDDK Tag)

This Recombinant SPATA18 protein is produced in HEK-293 Cells.
Catalog No. ABIN2732514
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for SPATA18 Protein (Myc-DYKDDDDK Tag) (ABIN2732514)

Target

See all SPATA18 Proteins
SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Protein Type

Recombinant

Origin

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 2
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This SPATA18 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human SPATA18 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    SPATA18 (Spermatogenesis Associated 18 (SPATA18))

    Alternative Name

    Spata18

    Background

    This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.

    Molecular Weight

    60.9 kDa

    NCBI Accession

    NP_660306
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