SPDEF/PSE Protein (Myc-DYKDDDDK Tag)
Quick Overview for SPDEF/PSE Protein (Myc-DYKDDDDK Tag) (ABIN2732544)
Target
See all SPDEF/PSE (SPDEF) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SPDEF/PSE protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SPDEF protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
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Alternative Name
- Spdef
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Background
- The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 37.3 kDa
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NCBI Accession
- NP_036523
Target
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