SPTLC1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Recombinant SPTLC1 protein expressed in HEK-293 Cells.
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Catalog No. ABIN2732627
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
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United States
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Quick Overview for SPTLC1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2732627)
Target
See all SPTLC1 Proteins
SPTLC1
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This SPTLC1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SPTLC1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (AA 43-143) protein (GST tag)
SPTLC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Alternative Name
- Sptlc1
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Background
- This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5&apos-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
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Molecular Weight
- 52.6 kDa
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NCBI Accession
- NP_006406
Target
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