SSB Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732688

This Recombinant SSB protein is produced in HEK-293 Cells.

Quick Overview for SSB Protein (Myc-DYKDDDDK Tag) (ABIN2732688)

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This SSB protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human SS-B / La protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SSB (Sjogren Syndrome Antigen B (SSB))

Alternative Name: Ss-B,la

Background: The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5&apos and 3&apos ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

Molecular Weight: 46.7 kDa

NCBI Accession: NP_003133