Stanniocalcin 1 Protein (STC1) (DYKDDDDK-His Tag)
Quick Overview for Stanniocalcin 1 Protein (STC1) (DYKDDDDK-His Tag) (ABIN2732755)
Target
See all Stanniocalcin 1 (STC1) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Stanniocalcin 1 protein is labelled with DYKDDDDK-His Tag.
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Characteristics
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- Recombinant human Stanniocalcin 1 / STC1 (C-term DDK/His tag) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 1 x PBS, pH 7.4, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Stanniocalcin 1 (STC1)
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Alternative Name
- Stanniocalcin 1,stc1
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Background
- This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
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Molecular Weight
- 26 kDa
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NCBI Accession
- NP_003146
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Pathways
- Hormone Activity
Target
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