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STARD4 Protein (His tag)

This Recombinant STARD4 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN2732766
$396.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for STARD4 Protein (His tag) (ABIN2732766)

Target

See all STARD4 Proteins
STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Protein Type

Recombinant

Origin

  • 4
  • 2
Human

Source

  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This STARD4 protein is labelled with His tag.

    Characteristics

    • Recombinant human STARD4 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the N-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

    Alternative Name

    Stard4

    Background

    Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1 MIM 184756) and by liver X receptors (e.g., LXRA MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008].

    Molecular Weight

    23.3 kDa

    NCBI Accession

    NP_631903
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