STK38 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732876

Recombinant STK38 protein expressed in HEK-293 Cells and has been mentioned in 1 publication.

Quick Overview for STK38 Protein (Myc-DYKDDDDK Tag) (ABIN2732876)

Target: STK38 (serine/threonine Kinase 38 (STK38))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This STK38 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human STK38 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: "Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages." in: Nature communications, Vol. 6, pp. 7167, (2015) (PubMed).

Target Details

Target: STK38 (serine/threonine Kinase 38 (STK38))

Alternative Name: Stk38

Background: This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.

Molecular Weight: 54 kDa

NCBI Accession: NP_009202