TADA3L Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733189

This Recombinant TADA3L protein is produced in HEK-293 Cells.

Quick Overview for TADA3L Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2733189)

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This TADA3L protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human TADA3L (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Alternative Name: Tada3l

Background: DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.

Molecular Weight: 41.2 kDa

NCBI Accession: NP_597814

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway