TCTN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for TCTN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2733402)
Target
See all TCTN1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This TCTN1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Tectonic-1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TCTN1 (Tectonic Family Member 1 (TCTN1))
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Alternative Name
- Tectonic-1
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Background
- This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which forms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 63.4 kDa
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NCBI Accession
- NP_001076006
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Pathways
- Tube Formation
Target
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