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TCAP Protein (His tag)

Recombinant TCAP protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2733416

Quick Overview for TCAP Protein (His tag) (ABIN2733416)

Target

See all TCAP Proteins
TCAP (Titin-Cap (Telethonin) (TCAP))

Protein Type

Recombinant

Origin

  • 3
  • 2
  • 1
Human

Source

  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This TCAP protein is labelled with His tag.

    Characteristics

    • Recombinant human Telethonin / TCAP (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
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    Expression System HEK-293 Cells
    Conjugate His tag
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the N-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    TCAP (Titin-Cap (Telethonin) (TCAP))

    Alternative Name

    Telethonin,tcap

    Background

    Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

    Molecular Weight

    18.9 kDa

    NCBI Accession

    NP_003664
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