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TCAP Protein (His tag)

Recombinant TCAP protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2733416
$396.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for TCAP Protein (His tag) (ABIN2733416)

Target

See all TCAP Proteins
TCAP (Titin-Cap (Telethonin) (TCAP))

Protein Type

Recombinant

Origin

  • 3
  • 2
  • 1
Human

Source

  • 2
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This TCAP protein is labelled with His tag.

    Characteristics

    • Recombinant human Telethonin / TCAP (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the N-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    TCAP (Titin-Cap (Telethonin) (TCAP))

    Alternative Name

    Telethonin,tcap

    Background

    Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

    Molecular Weight

    18.9 kDa

    NCBI Accession

    NP_003664
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