TNXB Protein (His tag)

Catalog No. ABIN2733418

This Recombinant TNXB protein is expressed in Escherichia coli (E. coli).

Quick Overview for TNXB Protein (His tag) (ABIN2733418)

Target: TNXB (Tenascin XB (TNXB))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This TNXB protein is labelled with His tag.

Characteristics:

• Recombinant human Tenascin-X / TNXB (full length, N-term HIS tag, transcript variant XB-S) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TNXB (Tenascin XB (TNXB))

Alternative Name: Tenascin-X,tnxb

Background: This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5&apos and 3&apos ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 73.8 kDa

NCBI Accession: NP_115859