TIMM8A/DDP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for TIMM8A/DDP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2733742)
Target
See all TIMM8A/DDP (TIMM8A) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This TIMM8A/DDP protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TIMM8A (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) protein (His tag)
custom-made TIMM8A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) protein (His tag)custom-made TIMM8A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-97) protein (His tag)TIMM8A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) (AA 1-72) protein (GST tag)TIMM8A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
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Alternative Name
- Timm8a
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Background
- This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Mar 2009]
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Molecular Weight
- 10.8 kDa
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NCBI Accession
- NP_004076
Target
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