TIMP2 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TIMP2 Protein (Myc-DYKDDDDK Tag) (ABIN2733766)
Target
See all TIMP2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TIMP2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TIMP2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Metalloproteinase Inhibitor 2 (TIMP2) (AA 27-220) (Active) protein (His tag)
TIMP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Metalloproteinase Inhibitor 2 (TIMP2) (AA 27-220) protein (GST tag)TIMP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Metalloproteinase Inhibitor 2 (TIMP2) protein (Fc Tag)TIMP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Metalloproteinase Inhibitor 2 (TIMP2) protein (His tag)TIMP2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Metalloproteinase Inhibitor 2 (TIMP2) (AA 30-220), (partial) protein (GST tag)TIMP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Alternative Name
- Timp2
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Background
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
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Molecular Weight
- 21.7 kDa
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NCBI Accession
- NP_003246
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Pathways
- cAMP Metabolic Process
Target
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