TLL1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733823

This Recombinant TLL1 protein is expressed in HEK-293 Cells.

Quick Overview for TLL1 Protein (Myc-DYKDDDDK Tag) (ABIN2733823)

Target: TLL1 (Tolloid-Like 1 (TLL1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This TLL1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human TLL1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TLL1 (Tolloid-Like 1 (TLL1))

Alternative Name: Tll1

Background: This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 114.5 kDa

NCBI Accession: NP_036596