TTR Protein (Myc-DYKDDDDK Tag)
Quick Overview for TTR Protein (Myc-DYKDDDDK Tag) (ABIN2734173)
Target
See all TTR ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TTR protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Transthyretin / Prealbumin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Transthyretin (TTR) (AA 21-147) protein (His tag)
TTR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transthyretin (TTR) (AA 21-147) protein (His tag)TTR Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transthyretin (TTR) (AA 23-147) protein (His tag)TTR Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transthyretin (TTR) (AA 21-147) protein (GST tag)TTR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Transthyretin (TTR) (AA 21-147) proteinTTR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TTR (Transthyretin (TTR))
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Alternative Name
- Transthyretin,prealbumin
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Background
- This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
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Molecular Weight
- 13.7 kDa
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NCBI Accession
- NP_000362
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Pathways
- Hormone Transport
Target
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