Tryptophan Hydroxylase 1 Protein (TPH1) (Myc-DYKDDDDK Tag)
Quick Overview for Tryptophan Hydroxylase 1 Protein (TPH1) (Myc-DYKDDDDK Tag) (ABIN2734414)
Target
See all Tryptophan Hydroxylase 1 (TPH1) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Tryptophan Hydroxylase 1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Tryptophan 5-hydroxylase 1 (TPH1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Tryptophan Hydroxylase 1 (TPH1)
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Alternative Name
- Tryptophan 5-Hydroxylase 1 (Tph1)
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Background
- This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
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Molecular Weight
- 50.8 kDa
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NCBI Accession
- NP_004170
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Pathways
- Feeding Behaviour
Target
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