Mps1 Protein (TTK) (Myc-DYKDDDDK Tag)
Quick Overview for Mps1 Protein (TTK) (Myc-DYKDDDDK Tag) (ABIN2734513)
Target
See all Mps1 (TTK) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Mps1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TTK protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Mps1 (TTK) (AA 1-856) protein (His tag)
custom-made TTK Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mps1 (TTK) (AA 1-857) protein (His tag)custom-made TTK Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mps1 (TTK) (AA 1-857) protein (GST tag)TTK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Mps1 (TTK) proteinTTK Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Mps1 (TTK)
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Alternative Name
- Ttk
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Background
- This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 96.9 kDa
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NCBI Accession
- NP_003309
Target
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